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Key Signals · 0 trials updated
- No new trial registrations, status transitions, results postings, or protocol amendments from any priority or tracked sponsor in the 2026-05-24 → 2026-05-25 window across all four query passes (molecule/condition, priority-sponsor any-phase, priority-sponsor P1, tracked-sponsor P2/3).
- Coverage note: the most recent registry posting day was Friday 2026-05-22, which carried 20 priority-sponsor (Novo/Lilly/Pfizer) updates in obesity/T2D — these fall OUTSIDE this run's strict 24h window and between scheduled runs (last run 2026-05-20). A catch-up scan of 2026-05-21 → 2026-05-24 may be warranted if runs are not daily.
- Query mechanics verified live (RANGE[2026-05-22,2026-05-25] returns 20 sponsor hits; RANGE[2026-05-24,2026-05-25] returns 0) — the empty result reflects a genuine weekend posting gap, not a broken query.
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No material signals — 2026-05-25
All four search passes returned zero studies for the last-24h window (AREA[LastUpdatePostDate]RANGE[2026-05-24,2026-05-25]):
1. Molecule/mechanism intervention query, Phase 2/3 → 0
2. Priority sponsors (Novo Nordisk, Eli Lilly, Pfizer), any status, all phases via condition → 0
3. Priority sponsors, Phase 1 → 0
4. Tracked sponsors (AstraZeneca, Boehringer Ingelheim, Amgen, Roche, Rhythm, Altimmune, Structure, Viking, Hanmi, Zealand), Phase 2/3 → 0
Why zero is real, not a query artifact
A sanity check on study counts shows the pipeline is healthy:
RANGE[2026-05-22,2026-05-25] → 20 priority-sponsor obesity/T2D studiesRANGE[2026-05-20,2026-05-25] → 23RANGE[2026-05-24,2026-05-25] → 0
So the in-scope updates cluster on Friday 2026-05-22, with nothing posted Saturday–Monday (2026-05-24/25). ClinicalTrials.gov posts on business days; the U.S. Memorial Day holiday weekend explains the gap.
Coverage gap flag (not acted on — window left per spec)
The durable Process defines a strict 24h window, which I have honored. However, the ~20 sponsor updates dated 2026-05-22 sit between the prior run (2026-05-20) and this one and are not captured by either run's 24h window. If this monitor is not run daily, those updates will be missed. Recommend either (a) running a one-off catch-up over 2026-05-21 → 2026-05-24, or (b) scheduling the monitor for every business day. I did not widen the window automatically, to preserve the process's audit trail.
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